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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha : |
23/12/2021 |
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Actualizado : |
23/12/2021 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
JORGE-SMEDING, E.; CARRIQUIRY, M.; CANTALAPIEDRA-HIJAR, G.; MENDOZA, A.; ASTESSIANO, A.L. |
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Afiliación : |
EZEQUIEL JORGE-SMEDING, Departamento de Producción Animal y Pasturas, Facultad de Agronomía, Universidad de la República, Montevideo, Uruguay.; MARIANA CARRIQUIRY, Departamento de Producción Animal y Pasturas, Facultad de Agronomía, Universidad de la República, Montevideo, Uruguay.; GONZALO CANTALAPIEDRA-HIJAR, INRAE, Université Clermont Auvergne, VetAgro Sup, UMRH, Saint-Genès-Champanelle, France.; ALEJANDRO FRANCISCO MENDOZA AGUIAR, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; ANA LAURA ASTESSIANO, Departamento de Producción Animal y Pasturas, Facultad de Agronomía, Universidad de la República, Montevideo, Uruguay. |
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Título : |
Plasma concentrations of branched-chain amino acids differ with Holstein genetic strain in pasture-based dairy systems.
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Fecha de publicación : |
2021 |
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Fuente / Imprenta : |
Scientific Reports, December 2021, Volume 11, Issue 1, Article number 22414. Open Access. doi: https://doi.org/10.1038/s41598-021-01564-0 |
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ISSN : |
2045-2322 |
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DOI : |
10.1038/s41598-021-01564-0 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received 11 May 2021; Accepted 09 September 2021; Published 17 November 2021.
Correspondence author: Astessiano, A.L.; Departamento de Producción Animal y Pasturas, Facultad de Agronomía, Universidad de la República, Av. Garzón 780, Montevideo, Uruguay; email:lauaste@gmail.com |
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Contenido : |
ABSTRACT -
In pasture-based systems, there are nutritional and climatic challenges exacerbated across lactation; thus, dairy cows require an enhanced adaptive capacity compared with cows in confined systems. We aimed to evaluate the effect of lactation stage (21 vs. 180 days in milk, DIM) and Holstein genetic strain (North American Holstein, NAH, n = 8; New Zealand Holstein, NZH, n = 8) on metabolic adaptations of grazing dairy cows through plasma metabolomic profiling and its association with classical metabolites. Although 67 metabolites were affected (FDR < 0.05) by DIM, no metabolite was observed to differ between genetic strains while only alanine was affected (FDR = 0.02) by the interaction between genetic strain and DIM. However, complementary tools for time-series analysis (ASCA analysis, MEBA ranking) indicated that alanine and the branched-chain amino acids (BCAA) differed between genetic strains in a lactation-stage dependent manner. Indeed, NZH cows had lower (P-Tukey < 0.05) plasma concentrations of leucine, isoleucine and valine than NAH cows at 21 DIM, probably signaling for greater insulin sensitivity. Metabolic pathway analysis also revealed that, independently of genetic strains, AA metabolism might be structurally involved in homeorhetic changes as 40% (19/46) of metabolic pathways differentially expressed (FDR < 0.05) between 21 and 180 DIM belonged to AA metabolism. © 2021, The Author(s). |
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Palabras claves : |
Dairy Cows; Early Lactation; Ketosis. |
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Asunto categoría : |
L02 Alimentación animal |
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URL : |
https://www.nature.com/articles/s41598-021-01564-0.pdf
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Marc : |
LEADER 02549naa a2200241 a 4500
001 1062621
005 2021-12-23
008 2021 bl uuuu u00u1 u #d
022 $a2045-2322
024 7 $a10.1038/s41598-021-01564-0$2DOI
100 1 $aJORGE-SMEDING, E.
245 $aPlasma concentrations of branched-chain amino acids differ with Holstein genetic strain in pasture-based dairy systems. .$h[electronic resource]
260 $c2021
500 $aArticle history: Received 11 May 2021; Accepted 09 September 2021; Published 17 November 2021. Correspondence author: Astessiano, A.L.; Departamento de Producción Animal y Pasturas, Facultad de Agronomía, Universidad de la República, Av. Garzón 780, Montevideo, Uruguay; email:lauaste@gmail.com
520 $aABSTRACT - In pasture-based systems, there are nutritional and climatic challenges exacerbated across lactation; thus, dairy cows require an enhanced adaptive capacity compared with cows in confined systems. We aimed to evaluate the effect of lactation stage (21 vs. 180 days in milk, DIM) and Holstein genetic strain (North American Holstein, NAH, n = 8; New Zealand Holstein, NZH, n = 8) on metabolic adaptations of grazing dairy cows through plasma metabolomic profiling and its association with classical metabolites. Although 67 metabolites were affected (FDR < 0.05) by DIM, no metabolite was observed to differ between genetic strains while only alanine was affected (FDR = 0.02) by the interaction between genetic strain and DIM. However, complementary tools for time-series analysis (ASCA analysis, MEBA ranking) indicated that alanine and the branched-chain amino acids (BCAA) differed between genetic strains in a lactation-stage dependent manner. Indeed, NZH cows had lower (P-Tukey < 0.05) plasma concentrations of leucine, isoleucine and valine than NAH cows at 21 DIM, probably signaling for greater insulin sensitivity. Metabolic pathway analysis also revealed that, independently of genetic strains, AA metabolism might be structurally involved in homeorhetic changes as 40% (19/46) of metabolic pathways differentially expressed (FDR < 0.05) between 21 and 180 DIM belonged to AA metabolism. © 2021, The Author(s).
653 $aDairy Cows
653 $aEarly Lactation
653 $aKetosis
700 1 $aCARRIQUIRY, M.
700 1 $aCANTALAPIEDRA-HIJAR, G.
700 1 $aMENDOZA, A.
700 1 $aASTESSIANO, A.L.
773 $tScientific Reports, December 2021, Volume 11, Issue 1, Article number 22414. Open Access. doi: https://doi.org/10.1038/s41598-021-01564-0
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INIA Las Brujas (LB) |
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| Registros recuperados : 10 | |
| 5. |  | GILSANZ, J.C.; ARBOLEYA, J.; MAESO, D.; PAULLIER, J.; BEYHAUT, E.; LAVANDERA, C.; SANDERS, D. C.; HOYT, G.D. Evaluation of limited tillage and cover crop systems to reduce N use and disease population in small acreage vegetable farms mirror image projects in Uruguay and North Carolina, USA. (Conference Paper). Acta Horticulturae, 30 june 2004, Nro.638, p.163-169. (Acta Horticulturae; 638) ISHS Acta Horticulturae 638: XXVI International Horticultural Congress: Sustainability of Horticultural Systems in the 21st Century. Editors: L. Bertschinger, J.D. Anderson.| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : B - 2 |
| Biblioteca(s): INIA Las Brujas. |
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| 8. | | SANDERS, D.C.; HOYT, G.; MONKS, D.; LOUWS, F.; GILSANZ, J.C.; ARBOLEYA, J.; PAULLIER, J.; MAESO, D. Mínimo laboreo y secuencias de cultivo en horticultura. In: INIA Las Brujas. Manejo conservacionista de los suelos en horticultura. Taller, 14 y 15 de marzo 2000, INIA Las Brujas. Canelones (UY), 2000. p. 51-53| Biblioteca(s): INIA Tacuarembó. |
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| 9. | | SANDERS, D.; HOYT, G.; MONKS, D.; LOUWS, F.; GILSANZ, J.C.; ARBOLEYA, J.; PAULLIER, J.; MAESO, D. Mínimo laboreo y secuencias de cultivo en horticultura. In: INIA Las Brujas. Manejo conservacionista de los suelos en horticultura. Taller, 14 y 15 de marzo 2000, INIA Las Brujas. Canelones (UY), 2000. p. 51-53| Biblioteca(s): INIA La Estanzuela; INIA Las Brujas. |
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| Registros recuperados : 10 | |
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